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Mouse Model Portfolio


Mouse Model Portfolio
Bmx-Cre-ERT2 Conditional, inducible Cre recombinase in arterial endothelial cells (Cre-ERT under Bmx promoter) deleter mouse
Conditional, inducible Cre recombinase in endothelial cells (Cre-ERT under VECad promoter) deleter mouse
Cyl-1-/- Cyclin D1 knockout mouse
Dll1flox Delta like-1 floxed conditional knockout mouse
DR3-/- DR3 (Death domain-containing TNFR 3) knockout mouse
Fgfr2bflox/flox Fgfr2 IIIb floxed conditional knockout mouse
GSTP1/2-/- Glutathione S-Transferase P1 and P2 double knockout mouse
GSTPNull x APCMin GSTP and APC Knock Out
Inv-a2b1 Human a2 and b1 integrin conditional transgenic mouse (epidermal expression), psoriasis model
Inv-a3b1 Human a3 and b1 integrin conditional transgenic mouse (epidermal expression), psoriasis model
Inv-a5b1 Human a5 and b1 integrin conditional transgenic mouse (epidermal expression), psoriasis model
Inv-a6b4 Human a6 and b4 integrin conditional transgenic mouse (epidermal expression)
InvEE Constituitively active MEK1 conditional transgenic mouse (epidermal expression), psoriasis model
Inv-IFNg Murine interferon-g conditional transgenic mouse (epidermal expression), systemic lupus erythematosus model
Jag1flox Jagged1 floxed conditional knockout mouse
K14deltaNbeta Beta-catenin N-terminal truncation transgenic mouse
K14delatNLef1 Lef1 N-terminal mutant transgenic mouse
K14MycER c-Myc protooncogene transgenic mouse
K5-R2b-null Fgfr2 IIIb conditional knockout mouse (epidermal knockout)
LFA-1-/- Lymphocyte Function-associated Antigen 1 knockout mouse
LSL-BrafD594A Conditional knockin (Cre-lox) D594A mutation of BRaf
LSL-B-raf-V600E B-Raf floxed conditional knockin mouse (V600E), oncogenic mutant
OGG1 Knockout Mouse
p23+/- p23+/- knockout mouse (70% reduction in p23 expressionin tissues)
Pdgrfb-Cre Conditional Cre recombinase in pericytes & vascular smooth muscle (Cre under Pdgrfb promoter) deleter mouse
Pik3ca Pi3Kinase C alpha knockin mouse (T208D, K227A), blocking Ras binding
Raf-1+/- Raf-1 knockout mouse
Raf-1D486A Raf-1 knockin mouse (D486A), oncogenic mutant
Raf-1FF/FF Raf-1 knockin mouse (Y340F Y341F), inactive mutant
SAP-1 Saposin-1 knockout mouse
TG4 Human MUC1 transgenic mouse
TREX-1 Knockout mouse
Ung-/- Uracil DNA Glycosylase knockout mouse
 
For further information about mouse models from CRT, or to discuss supply or licensing options, please contact us at reagents@cancertechnology.com

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