| Knockout / Knockin Mouse Models |
| Cyl-1-/- |
Cyclin D1 knockout mouse |
| DR3-/- |
DR3 (Death domain-containing TNFR 3) knockout mouse |
| GSTP1/2-/- |
Glutathione S-Transferase P1 and P2 double knockout mouse |
| GSTPNull x APCMin |
GSTP and APC Knock Out |
| LFA-1-/- |
Lymphocyte Function-associated Antigen 1 knockout mouse |
| LSL-BrafD594A |
Conditional knockin (Cre-lox) D594A mutation of BRaf |
| OGG1 Knockout Mouse |
| p23+/- |
p23+/- knockout mouse (70% reduction in p23 expressionin tissues) |
| Pik3ca |
Pi3Kinase C alpha knockin mouse (T208D, K227A), blocking Ras binding |
| Raf-1+/- |
Raf-1 knockout mouse |
| Raf-1D486A |
Raf-1 knockin mouse (D486A), oncogenic mutant |
| Raf-1FF/FF |
Raf-1 knockin mouse (Y340F Y341F), inactive mutant |
| SAP-1 |
Saposin-1 knockout mouse |
| Ung-/- |
Uracil DNA Glycosylase knockout mouse |
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| Conditional Knockout / Transgenic Mouse Models |
| Dll1flox |
Delta like-1 floxed conditional knockout mouse |
| Fgfr2bflox/flox |
Fgfr2 IIIb floxed conditional knockout mouse |
| Inv-a2b1 |
Human a2 and b1 integrin conditional transgenic mouse (epidermal expression), psoriasis model |
| Inv-a3b1 |
Human a3 and b1 integrin conditional transgenic mouse (epidermal expression), psoriasis model |
| Inv-a5b1 |
Human a5 and b1 integrin conditional transgenic mouse (epidermal expression), psoriasis model |
| Inv-a6b4 |
Human a6 and b4 integrin conditional transgenic mouse (epidermal expression) |
| InvEE |
Constituitively active MEK1 conditional transgenic mouse (epidermal expression), psoriasis model |
| Inv-IFNg |
Murine interferon-g conditional transgenic mouse (epidermal expression), systemic lupus erythematosus model |
| Jag1flox |
Jagged1 floxed conditional knockout mouse |
| K14deltaNbeta |
Beta-catenin N-terminal truncation transgenic mouse |
| K14deltaNLef1 |
Lef1 N-terminal mutant transgenic mouse |
| K14MycER |
c-Myc protooncogene transgenic mouse |
| K5-R2b-null |
Fgfr2 IIIb conditional knockout mouse (epidermal knockout) |
| LSL-B-raf-V600E |
B-Raf floxed conditional knockin mouse (V600E), oncogenic mutant |
| TG4 |
Human MUC1 transgenic mouse |
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| Deleter (Recombinase) Mouse Strains |
| Bmx-Cre-ERT2 |
Conditional, inducible Cre recombinase in arterial endothelial cells (Cre-ERT under Bmx promoter) deleter mouse |
| Pdgrfb-Cre |
Conditional Cre recombinase in pericytes & vascular smooth muscle (Cre under Pdgrfb promoter) deleter mouse |
| VECad-Cre-ERT2 |
Conditional, inducible Cre recombinase in endothelial cells (Cre-ERT under VECad promoter) deleter mouse |
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For further information about mouse models from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com
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