| Relevance : |
In vitro study and comparison of genetic instability in myeloma tumour lines (homoplastic with JIM3); in vitro study of effects of DNA repair deficiency in myeloma tumour lines |
| Description : |
JIM1 myeloma tumour line demonstrating typical plasma cell phenotype (CD38, PCA-1 8A, CD24 positive), deficient in DNA repair |
| Cell Line Type / Application : |
Tumour line |
| Species / Origin : |
Human; derived from plasma myeloma cells derived from pleural fluid of advanced multiple myeloma patient, homoplastic with JIM3 |
| Growth / Phenotype Keywords : |
Plasma cell phenotype |
| Disease Keywords : |
Cancer; myeloma |
| Recommended Growth Conditions : |
JIM1 cell line can be grown in Dexter culture medium, consisting of Fischer's medium with 20% FCS, penicillin (100U/ml), streptomycin (100mg/ml), fungizone (0.0125mg/ml), hydrocortisone sodium succinate (10-7 M) |
| References : |
Hamilton MS et al, Leukemia, 1991, v5 pp768-771 
Velangi MR et al, Carcinogenesis, 2004, v25 pp1795-1803 |
| Notes : |
For more multiple myeloma tumour lines, see also;
JIM3 cell line |
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