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Biological Therapeutics

From patented antibodies to tumour associated cell surface markers. We have a diverse portfolio with the opportunity to licence agents in pre-clinical to Phase II clinical development.

This opportunity has produced a lead T-Cell Receptor mimic (TCRm) monoclonal antibody (mAb) against an HLA-A*0201 presented peptide derived from the cancer target p53, that is mutated in 50% of hum

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To develop a novel IGF pathway therapeutic for treatment of a range of tumours that are associated with gain of function of IGF2 including hepatocellular carcinoma, sarcomas, adrenocortical carcino

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A summary of all of CRT's antibody and peptide opportunities can be found in the presentation linked below.

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CRT is seeking a commercial partner for licensing and/or collaborative development of potential best-in-class therapeutic anti-CCR4 antibodies.

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The anti-TACE antibody comes with an extensive package of data demonstrating high affinity binding, potent inhibitory action against TACE in vitro and in vivo, a long in vivo halflife and in vivo e

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