| Antigen: |
XRCC2 |
| Relevance: |
XRCC2
(X-Ray Repair Cross Complementing 2) is a RAD51
paralog. RAD51 is a eukaryotic homologue
of E. coli
RecA, a recombinase, and a component of the homologous
recombination DNA repair
pathway. RAD51 forms
a nucleoprotein filament (through binding RAD52 and
single stranded DNA that are exposed following double
strand breaks) that initiates recombination. XRCC2
is also components of the homologous recombination pathway.
|
| Clone: |
XRCC2 1G4/1 |
| Subclass: |
IgG1 |
| Applications: |
Western blot |
| Immunogen: |
- |
| Reactivity: |
Human and Hamster |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
French CA et al. 2002.
J. Biol. Chem. 277(22):19322-330  |
| Notes: |
Positive control: HeLa nuclear extracts. Specfic- does not recognise other paralogs. 33 kDa MW |
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