| Antigen: |
XPA |
| Relevance: |
XPA binds to the replication protein A (RPA) and is a core component of the nucleotide excision repair pathway. XPA is involved in one of the complementation groups of the heritable condition Xeroderma pigmentosum, where defects in nucleotide excision repair result in increased susceptibility to mutagens including UV. |
| Clone: |
2A4 |
| Subclass: |
IgG1 |
| Applications: |
Western blot, Immunohistochemistry |
| Immunogen: |
HIS-tagged recombinant human XPA protein. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
- |
| Notes: |
Works on pure and partially purified protein, but not on crude cell extract. Can be used for nuclear staining of XPA in human cells. |
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