| Antigen: |
XPA |
| Relevance: |
XPA binds to the replication protein A (RPA) and is a core component of the nucleotide excision repair pathway. XPA is involved in one of the complementation groups of the heritable condition Xeroderma pigmentosum, where defects in nucleotide excision repair result in increased susceptibility to mutagens including UV. |
| Clone: |
5A2 |
| Subclass: |
IgG1 |
| Applications: |
Western blot |
| Immunogen: |
HIS-tagged recombinant human XPA protein. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
- |
| Notes: |
Positive control: LS174T or MCF-7 cells or human tonsil. About 40 kDa MW. |
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