| Antigen: |
Rad51B |
| Relevance: |
RAD51B
is a Rad51 paralog. RAD51 is a eukaryotic homologue
of E. coli
RecA, a recombinase, and a component of the homologous
recombination DNA repair
pathway. RAD51 forms
a nucleoprotein filament (through binding RAD52 and
single stranded DNA that are exposed following double
strand breaks) that initiates recombination. RAD51B
is also a component for the homologous recombination
pathway. |
| Clone: |
rad51b 1h3/13 |
| Subclass: |
IgG2a |
| Applications: |
Western |
| Immunogen: |
Raised against his-tagged human Rad51B, overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page |
| Reactivity: |
- |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Masson J-Y et al. 2001.
Genes Dev. 15:3296-3307 
Albala JS et al. 1997. Genomics 46:476-479 |
| Notes: |
Does not recognise Rad51C in total HeLa extracts. |
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