| Antigen: |
p53 N terminal- linear
epitope aa 10-16 |
| Relevance: |
p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. |
| Clone: |
DO-2 |
| Subclass: |
IgG1 |
| Applications: |
Western blot, Immunoprecipitation, Immunohistochemistry (frozen, parafin embedded) |
| Immunogen: |
- |
| Reactivity: |
Human |
| Species raised in: |
- |
| Fusion partner: |
- |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Vojtesek B et al. 1992.
J. Immunol. Methods. 151(1-2): 237-44 
Stephen CW et al. 1995. J Mol. Biol. 248(1): 58-78.  |
| Notes: |
Positive control: MDA-MB-231
cell line. |
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