| Antigen: |
p53. Cross reacts with murine epitope in Ct region between residues 306-393 wild type & mutant |
| Relevance: |
p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. |
| Clone: |
PAB 1802 |
| Subclass: |
IgG1 |
| Applications: |
Immunoprecipitation, Western blot, Immunohistochemistry (frozen sections or parafin treated with pepsin), ELISA |
| Immunogen: |
p53-beta galactosidase fusion protein |
| Reactivity: |
Human, Mouse |
| Species raised in: |
Mouse |
| Fusion partner: |
NS-1 |
| Recommended growth conditions: |
DMEM 5% FCSDMEM 5% FCS |
| References: |
Banks L et al. 1986. Eur. J. Biochem. 159(3):529-534. |
| Notes: |
50 kDa MW. Positive control:
MDA-MB-231 cell line |
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