| Antigen: |
Neural Cell Adhesion Molecule (NCAM; CD56) |
| Relevance: |
Neural cell adhesion molecule (NCAM) is a cell-surface glycoprotein and member of the neural adhesion molecule family of the immunoglobulin superfamily. NCAM is implicated in the development of the nervous system. |
| Clone: |
ERIC-1 |
| Subclass: |
IgG1 |
| Applications: |
Immunoprecipitation, Western
blot, ELISA, Radioimmunoassay, Immunohistochemistry
(Acetone Fixed, Frozen) |
| Immunogen: |
Retinoblastoma tissue membrane fraction. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
P3x63-Ag8.653 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Bourne
SP et al. 1991. J. Neurooncol. 10:111-119. 
Phimister
E et al. 1991. J. Clin. Pathol. 44:580-585. |
| Notes: |
In the mouse brain, 3 main isoforms have been described of 180,140 and 120 kDa MW. A Western blot of 2 year old pediatric brain revealed bands of 180,140 and 120 kDa (weakly) with ERIC-1. Positive control: neuroblastome. |
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