| Antigen: |
MRP-8 |
| Relevance: |
MRP-8 and MRP-14 are cytosolic calcium-binding proteins of 8kDa and 14kDa that form a heterodimer. MRP-8 and MRP-14 are expressed in peripheral blood monocytes, neutrophils and keratinocytes (mature). Expression is lost on tissue maturation of monocytes to macrophages. MRP-14 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites. |
| Clone: |
MRP8 7C12/4 |
| Subclass: |
IgM |
| Applications: |
Western, ELISA, FACS |
| Immunogen: |
recombinant Human MRP8 |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Robinson MJ et al. 2002. J. Biol. Chem. 277(5):3658-65.  |
| Notes: |
Positive control: neutrophil lysate (particularly neutrophils from spleen) |
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