| Antigen: |
Mast cells |
| Relevance: |
MCG25 is useful for mast cell identification in immunological reactions and hypersensitivity diseases e.g. allergy and asthma. Antigen is found in granule components of mast cells. |
| Clone: |
MCG35 |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemistry (Acetone Fixed, Frozen) |
| Immunogen: |
Spleen cells and bone marrow cells (erythrocyte depleted) from a patient with systemic mastocytosis. The bone marrow preparation consisted of 50% typical mast cells. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
X63.Ag8.653 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Rimmer
E et al. 1984. J. Clin. Pathology. 37:1249-1255. 
Rimmer E
& Horton M. 1987. Clin. Exp. Immunol. 68:712-718.
|
| Notes: |
The antibody does not react with basophils or other haemopoietic cell types. Not reactive on fixed tissue. |
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