| Antigen: |
L1 cell adhesion molecule (L1CAM; CD171) |
| Relevance: |
L1 cell adhesion molecule
(L1CAM) is a cell-surface glycoprotein and member of
the neural adhesion molecule family of the immunoglobulin
superfamily. L1CAM is implicated in the development
of the nervous system and its expression is restricted
to tissues arising from the neuroectoderm. L1CAM is
present on tumours of neuroectodermal and glial origin
(e.g. neuroblastoma and schwannomas). UJ127.11 may be
useful in the diagnosis of embryonic tumours (e.g. neuroblastoma). |
| Clone: |
UJ127.11 |
| Subclass: |
IgG1 |
| Applications: |
Western blot, Immunoprecipitation |
| Immunogen: |
Homogenous suspension
of 16 week human foetal brain |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Female Balb/c |
| Fusion partner: |
P3-X63-Ag8-563 |
| Recommended growth conditions: |
DMEM + 5%FCS |
| References: |
Kemshead JT et al. 1983. Int. J. Cancer 31:187-195 
Patel K et al. 1990. Biochem. Soc. Transactions. 18:274 |
| Notes: |
- |
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Please note that CRT supplies to distributors only. However, we are happy to direct researchers to the appropriate commercial party to obtain antibodies within our portfolio. Click here to view disclaimer information. |
