| Antigen: |
Keratin 18 |
| Relevance: |
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. |
| Clone: |
LDK18 |
| Subclass: |
IgG1 |
| Applications: |
Western blot, ELISA |
| Immunogen: |
Synthetic peptide of human keratin 18 (CSETNDTKVLRH-COOH) |
| Reactivity: |
Human, Mouse, Potoroo |
| Species raised in: |
Mouse |
| Fusion partner: |
- |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
- |
| Notes: |
Positive control: Stains simple epithelial cells, all of which express Keratin 18 |
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