| Antigen: |
Keratin 7 human; possibly some reaction with keratin 8. |
| Relevance: |
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. |
| Clone: |
LP5K |
| Subclass: |
IgG2b |
| Applications: |
Western blot, Immunohistochemistry (paraffin embedded) |
| Immunogen: |
Sonicated cytoskeleton fractions ( insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes. |
| Reactivity: |
- |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0-Ag14 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Lane, E.B.
et al. 1985 Ann. NY Acad. Sci. 455: 241-258 
Markey, A.
et al. 1991 J.Invest.Dermatol. 97(5): 763-770
|
| Notes: |
54 kDa MW |
For further information about antibodies from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com
Please note that CRT supplies to distributors only. However, we are happy to direct researchers to the appropriate commercial party to obtain antibodies within our portfolio. Click here to view disclaimer information. |
