| Antigen: |
Keratin 19 (a cytokeratin) |
| Relevance: |
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 19 is the smallest human keratin and is found in many simple and some non-keratinising stratified squamous epithelia. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7. |
| Clone: |
BA16 |
| Subclass: |
IgG1 |
| Applications: |
Western blot, Immunohistochemistry (Acetone Fixed, Frozen) |
| Immunogen: |
Detergent-insoluble extract of human mammary epithelial organoids. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
X63-Ag-8.653 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Bartek
J et al. 1985. J. Cell Sci. 75:17-33. 
Bartek J
et al. 1985. Int. J. Cancer. 36:299-306.
|
| Notes: |
40 kDa MW |
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