| Antigen: |
Keratin 15 (a cytokeratin) |
| Relevance: |
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 15 is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. |
| Clone: |
LHK 15 |
| Subclass: |
IgG2a |
| Applications: |
Immunohistochemistry (Paraffin embedded, Acetone Fixed, Frozen), ELISA, Western |
| Immunogen: |
Peptide sequence of cytokeratin 15 - BSA conjugate |
| Reactivity: |
Human, Mouse, Rat, Bovine |
| Species raised in: |
- |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
5-10%FCS in DMEM |
| References: |
Waseem
A et al. 1999. J. Invest. Dermatol. 112:362-369 
Porter RM
et al. 2000. Lab Invest. 80(11):1701-10
|
| Notes: |
- |
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