| Antigen: |
ICAM-3 (CD50). |
| Relevance: |
ICAMs are members of the
immunoglobulin superfamily that is characterised by
the presence of immunoglobulin-like domains. ICAM-3
is the major ligand for LFA-1 (CD11a/CD18) in the resting
state. ICAM-3 may play a key role in initiating
immune responses. ICAM 3.1 and ICAM 3.2 can be
used to examine LFA-1/ICAM-3 adhesion. |
| Clone: |
ICAM 3.1 |
| Subclass: |
IgG1 |
| Applications: |
Immunoprecipitation, Western blot, Radioimmunoassay, ELISA, FACS, Immunohisotchemistry (Frozen) |
| Immunogen: |
ICAM-3Fc chimeric fusion
protein |
| Reactivity: |
- |
| Species raised in: |
Mouse |
| Fusion partner: |
Sp2 |
| Recommended growth conditions: |
DMEM + 5% FCS |
| References: |
Holness
CL et al. 1995. J. Biol. Chem. 270(2): 877-884 
Bossy D et al. 1995. Eur. J. Immunol. 25(2):459-465
|
| Notes: |
western gives a 130KD band |
For further information about antibodies from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com
Please note that CRT supplies to distributors only. However, we are happy to direct researchers to the appropriate commercial party to obtain antibodies within our portfolio. Click here to view disclaimer information. |
