| Antigen: |
ICAM-1(CD54) |
| Relevance: |
ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). P1W16 may be useful for prognosis of malignant melanoma |
| Clone: |
P1W16 |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemistry (Paraffin embedded), Immunoprecipitation, FACS, Immunofluorescence |
| Immunogen: |
V(+)B2- Human Ocular melanoma line |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
- |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
- |
| Notes: |
Positive control lysate: A375M melanoma cell line or tonsil. 85-115 kDa MW |
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