| Antigen: |
HPV-16 L1 (major capsid protein L1) |
| Relevance: |
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases, and HPV-1, which is associated with benign cutaneous warts. HPV late protein L1 is the major capsid protein. CamVir-1 reacts very strongly with biopsy specimens containing HPV-16 or HPV-33, but very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. Cross-reacts with HPV-37. |
| Clone: |
CamVir 1 |
| Subclass: |
IgG2a |
| Applications: |
Western blot, Immunoprecipitation, Immunohistochemistry (Paraffin embedded) |
| Immunogen: |
A β-galactosidase-L1 fusion protein (containing amino acids 198-C terminus of HPV-16 L1) purified by acrylamide gel electrophoresis. |
| Reactivity: |
- |
| Species raised in: |
- |
| Fusion partner: |
NSO |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
McLean C et al. 1990.
J. Clin. Pathol. 43:488-492 
Zhang W et al. Virology. 1998 Apr 10;243(2):423-31 |
| Notes: |
The antibody reacts with a 56 kDa protein in cells infected with L1-vaccinia virus. Cross reacts with hpv37 |
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