| Antigen: |
HLA-DR16, 103, 11, 12, 13, 8, 7, 4 (Dw10 only), DR51 (DR15 associated). |
| Relevance: |
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 16.1 is useful for distinguishing DR1 homozygotes from DR1, DR103 heterozygotes. |
| Clone: |
TAL 16.1 |
| Subclass: |
IgG2a |
| Applications: |
ELISA, FACS, Western blot, Immunohistochemistry (Paraffin embedded) |
| Immunogen: |
C3H mouse L cells transfected with the HLADRB5*0101 gene |
| Reactivity: |
Human |
| Species raised in: |
Mouse |
| Fusion partner: |
NSO/U |
| Recommended growth conditions: |
RPMI 1640 + 10% FCS |
| References: |
Sadler A et al. 1993. Tissue Antigens. 41:42-46 
Munksgaard. 1993. Immunogenetics. 32:51-55 |
| Notes: |
Cytotoxic with rabbit complement. Western blots to dimer and DR beta chain. 29 kDa MW |
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