| Antigen: |
HLA-DR ß chain 1 (1st
domain, monomorphic). HLA class II. |
| Relevance: |
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. |
| Clone: |
DA2 |
| Subclass: |
IgG1 |
| Applications: |
Western blot, ELISA, FACS Immunohistochemistry(Frozen) |
| Immunogen: |
The membranes of LKT cells ( a B lymphoblastoid cell line) |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
P3.X63.Ag8 |
| Recommended growth conditions: |
RPMI 1640 + 10% FCS. |
| References: |
Brodsky F et al. 1979. Immunol. Rev. 47:3-61. 
Brodsky F et al. 1980. Tissue Antigens. 16:30-48. |
| Notes: |
Not cytotoxic. Western blots to dimer and beta chain. All DR and DP except DR7. Not specific to humans. |
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