| Antigen: |
HLA-DR; recognises all
HLA-DR except DR3 and DR52. HLA Class II a /ß dimer.
|
| Relevance: |
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 15.1 is useful for distinguishing DR3 homozygotes from DR3, DR6 heterozygotes. |
| Clone: |
TAL 15.1 |
| Subclass: |
IgG2a |
| Applications: |
ELISA, FACS, Western blot, Radioimmunoassay |
| Immunogen: |
L cells transfected with DR a b chain cDNA from a cell line homozygous for HLA-DR8. |
| Reactivity: |
Human |
| Species raised in: |
- |
| Fusion partner: |
P3/NS1/1-Ag4-1 |
| Recommended growth conditions: |
RPMI 1640 + 10% FCS |
| References: |
Madrigal JA et al. 1989. J. Immunol. 143:4084-4089  |
| Notes: |
Cytotoxic with rabbit complement. 70kDa MW |
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