| Antigen: |
HLA-DP alpha (and DQ to
a lesser extent). |
| Relevance: |
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. TAL 3C3 is reactive on fixed tissue, reacts to class II antigens and cross-reacts with smooth muscle. Not cytotoxic with rabbit complement. |
| Clone: |
TAL 3C3 |
| Subclass: |
IgG1 |
| Applications: |
Radioimmunoassay, Immunohistochemistry, Western blot |
| Immunogen: |
Bristol 8 separated alpha chain preparation. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
P3/NS1/1-Ag4-1 |
| Recommended growth conditions: |
Culture medium: RPMI 1640 + 10% FCS |
| References: |
Adams T et al. 1983. Immunol. 50(4):613-624 
Thomas A et al. 1988. J. Pathol. 154:353-363 |
| Notes: |
Western blots to alpha chain only, not dimer. 33Kd MW a chain subunit precipitated after SDS denaturation. |
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