| Antigen: |
c-erbB3 (Her3) intracellular
domain |
| Relevance: |
The EGFR family of type
I growth factor receptor tyrosine kinases includes EGFR
(HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4
(HER4). c-erbB3
is normally found in non-dividing differentiated epithelial
cells, neurones and hepatocytes. It has approximately
80% prevalence in a wide variety of tumours of the gastro-intestinal
tract, and approximately 20% prevalence in breast cancer.
|
| Clone: |
RTJ1 |
| Subclass: |
IgM |
| Applications: |
Immunohistochemistry (Paraffin embedded), Western blot, Immunoprecipitation |
| Immunogen: |
Peptide from Ct of human c-erB-3 |
| Reactivity: |
Human |
| Species raised in: |
- |
| Fusion partner: |
NSO |
| Recommended growth conditions: |
RPMI 1640 10% FCS |
| References: |
Rajkumar T et al. 1993.
J. Pathol. 170(3):271-278 
Srinivasan et al. 1998. J. Pathol. 185:236-245 |
| Notes: |
Immunoblotting: 2 unident bands |
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