| Antigen: |
c-erb B3 (Her3) extracellular domain |
| Relevance: |
The EGFR family of type
I growth factor receptor tyrosine kinases includes EGFR
(HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4
(HER4). c-erbB3
is normally found in non-dividing differentiated epithelial
cells, neurones and hepatocytes. It has approximately
80% prevalence in a wide variety of tumours of the gastro-intestinal
tract, and approximately 20% prevalence in breast cancer.
|
| Clone: |
SGP1 |
| Subclass: |
IgGI k |
| Applications: |
Immunoprecipitation, FACS |
| Immunogen: |
c-erb B3 protein from transfected human kidney fibroblasts purified by wheatgerm lectin affinity chromatography |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
NS0 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Rajkumar T et al. 1994.
Br. J. Cancer. 70:459-465 
Rajkumar T et al. 1995. The Breast. 4: 84-91
Srinivasan R et al. 1998. J. Pathol. 185:236-245 |
| Notes: |
- |
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