| Antigen: |
Epidermal growth factor receptor (EGFR); Her1. Intracellular domain (aa 985-996) |
| Relevance: |
The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). EGFR is overexpressed in many common solid human squamous cell carcinomas. |
| Clone: |
F4 |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemistry(Acetone Fixed, Frozen, Paraffin embedded), Immunoprecipitation, Radioimmunoassay, ELISA |
| Immunogen: |
Synthetic peptide (aa 985 to 996 of human EGFR) coupled to keyhole limpet hemocyanin. |
| Reactivity: |
- |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
NS-1 |
| Recommended growth conditions: |
RPMI 1640 + 5% FCS |
| References: |
Gullick WJ et al. 1986. Cancer Res. 46:285-292. 
Berger MS et al. 1987. J. Pathol. 152:297- 307. |
| Notes: |
Use: Research on relevance of growth factor receptors to loss of growth control in tumours. |
For further information about antibodies from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com
Please note that CRT supplies to distributors only. However, we are happy to direct researchers to the appropriate commercial party to obtain antibodies within our portfolio. Click here to view disclaimer information. |
