| Antigen: |
CD8 (Leu-2) |
| Relevance: |
CD8 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. CD8 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. M236 is useful for the identification of cytotoxic/suppressor cell subpopulation in peripheral blood, elimination of cytotoxic/suppressor cell subpopulation from peripheral blood and bone marrow, elimination of some T cell leukaemias and blocking of cytotoxic activity |
| Clone: |
M236 |
| Subclass: |
IgG1 |
| Applications: |
Radioimmunoassay, Immunoprecipitation |
| Immunogen: |
MOLT 4 cell line |
| Reactivity: |
- |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
NS1 |
| Recommended growth conditions: |
DMEM + 5% FCS |
| References: |
1st International Workshop
on Human Leucocyte Differentiation Antigans (code T67),
Paris, November 1982 |
| Notes: |
The antigen is a 32kDa MW protein. |
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