| Antigen: |
CD64 |
| Relevance: |
CD64 is an IgG receptor expressed by monocytes and myeloid cell lines. 10.1 blocks Ig binding to FcR1 receptor, may block ADCC. It is an indicator of inflammation. Increased expression of FcR1 on monocytes after interferong treatment. |
| Clone: |
10.1 |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemistry, FACS, Immunoprecipitation |
| Immunogen: |
Rheumatoid synovial fluid cells and fibronectin purified human monocytes. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0-Ag14 |
| Recommended growth conditions: |
DMEM + 5% FCS. |
| References: |
Dougherty et al. 1987.
Eur. J. Immunol. 17:1453-1459 
Jayaram Y et al. 1989. Clin. Exp. Immunol. 75:414  |
| Notes: |
71 kDa MW. Positive control: myeloid cell lines U937 and HL60 |
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