| Antigen: |
Leu 1 (CD5) |
| Relevance: |
CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. UCH-T2 is useful for detection of T cells in peripheral blood and lymph nodes and categorisation of T cell lymphomas and B cell chronic lymphocytic leukaemia. |
| Clone: |
UCH-T2 |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemistry (frozen sections), Immunofluorescence |
| Immunogen: |
Thymocytes followed by
Sezary T cells |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
- |
| Recommended growth conditions: |
RPMI + 7.5% FCS |
| References: |
Beverley P & Callard
R. 1982. Protides Biol. Fluids. 29:653-658 |
| Notes: |
Use: Immunofluorescence and immunostaining frozen, enrichment of T cell populations by cell sorting or panning. |
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