| Antigen: |
CD35 (Human complement
receptor 1; CR1) |
| Relevance: |
CD35 is found on many leucocytes and binds C3b and C4b. E11 detects the C3b/C4b receptor present on most leukemic monoblasts and also normal granulocytes, but which is not expressed on leukemic myoblasts. Used to define B cell lymphomas. |
| Clone: |
E11 |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemsitry (Acetone Fixed, Frozen) Immunoprecipitation |
| Immunogen: |
Acute monocytic leukaemia
cells and normal blood monocytes |
| Reactivity: |
human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
P3-NS1/1-Ag4-1 |
| Recommended growth conditions: |
DMEM + 5% FCS |
| References: |
Hogg N et al. 1984. Eur.
J. Immunol. 14:236-243 
Leucocyte Typing III. Edited by AJ McMichael et al.
1987 |
| Notes: |
- |
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