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Anti-Plasma cell Antibody Profile

Antigen: Plasma cells
Relevance: Plasma cells are antibody secreting cells found in the lymphoid tissue and derived from B cells.  LIV 3G11 reacts with normal and malignant plasma cells but not with normal B cells
Clone: LIV3G11
Subclass: IgG2a
Applications: Immunohistochemistry (formalin fixed)
Immunogen: Pancreatic cancer related serum mucin
Reactivity: Human
Species raised in: Mouse
Fusion partner: -
Recommended growth conditions: DMEM + 5% FCS
References:

Ching CK and Rhodes JM. 1988. J Gastroenterology. 95: 137-42 PubMed Logo

Ching CK and Rhodes JM. 1990. In J Cancer. 45: 1022-27 (describes immunogen) PubMed Logo

Notes: LIV3G11 shows a very high degree of specificitiy for plasma cells.  Positive control: tonsil or lymph node
Image: Immunohistochemistry on human colon (formalin fixed)
 

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