| Antigen: |
TCP-1 (T-complex polypeptide-1; CCTalpha) |
| Relevance: |
TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. |
| Clone: |
84a |
| Subclass: |
IgG2a |
| Applications: |
Western blot, Immunoprecipitation |
| Immunogen: |
C-terminal half of the full length murine TCP protein |
| Reactivity: |
Mouse, Chicken, Hamster, Monkey, Human |
| Species raised in: |
Rat |
| Fusion partner: |
Y3 Ag 1.2.3 |
| Recommended growth conditions: |
- |
| References: |
Willison K et al. 1989. Cell. 57: 621-632 
Harrison-Lavoie et al. 1993. EMBO J . 12 : 2847-2853 |
| Notes: |
Epitope: 542 HGSYE (in the C terminus). 84a can be used together with 91a for immunoprecipitation of CCT. 84a recognises a protein of 80kDa in LK-35.2 cells |
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