| Antigen: |
AP-2α; does not
react with AP-2γ and β forms |
| Relevance: |
AP-2 is a family of developmentally
regulated transcription factors, which also play a role
in breast cancer and melanoma. The
AP-2 transcription factors form the OB2 complex that
has been shown to up-regulate c-erb-B2 transcription. |
| Clone: |
AP2a 8G8/5 |
| Subclass: |
IgG1 |
| Applications: |
Western blot, Immunohistochemistry (Paraffin embedded) |
| Immunogen: |
Bacterial AP-2α/AP-2γ
fusion protein |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM + 5% FCS |
| References: |
- |
| Notes: |
Antigen recovery using
microwave or pressure cooking required for paraffin
embedded tissue. Positive control: extract from
breast cancer cell line ZR75-1. Western blots at 50
KDa |
| Image: |
Immunohistochemistry on formalin fixed paraffin embedded breast tissue section |
| |
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