| Antigen: |
Ufd1 Directed against a 40kd protein interacting with the ATPase p97 involved in membrane fusion |
| Relevance: |
The Ufd1 protein (human gene: UFD1L) forms a heterodimer with another protein, Npl4. Ufd1-Npl4 serves as an ubiquitin-adapter for the VCP/p97 AAA ATPase. The ATPase complex is required for endoplasmic reticulum-associated degradation and regulation of spindle dynamics, and nuclear envelope formation after mitosis. |
| Clone: |
5e2 |
| Subclass: |
|
| Applications: |
Western Blot, ELISA, Immunoprecipitation, Immunofluorescence |
| Immunogen: |
Full length mouse Ufd1 expressed in E coli was used as immunogen. |
| Reactivity: |
Human, Xenopus |
| Species raised in: |
Balb/c |
| Fusion partner: |
Sp2/0Ag.14 |
| Recommended growth conditions: |
|
| References: |
Hetzer et al., 2001. Nature Cell Biology. 3, 1086 - 1091. 
Cao et al, 2003. Cell, 115(3), 355-367
Meyer et al., 2000. EMBO J. 19, pp. 2181-2192. |
| Notes: |
|
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