| Antigen: |
SV40 large T antigen |
| Relevance: |
SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. |
| Clone: |
LP7N |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemistry (frozen sections) |
| Immunogen: |
Detergent insoluble fraction of SVK14 cell line (SV40 transformed neonatal keratinocytes) |
| Reactivity: |
SV40 |
| Species raised in: |
- |
| Fusion partner: |
- |
| Recommended growth conditions: |
DMEM 5% FCS |
| Epitope: |
Epitope has been mapped to a region of the SV40 T antigen which is not covered by small t-shared domain or ND2 protein, since both are negative. Epitope is denaturation-sensitive and does not immunoblot. |
| References: |
- |
| Notes: |
- |
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