| Antigen: |
HRX (MLL, ALL-1, Htrx) |
| Relevance: |
The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners |
| Clone: |
HRX107 |
| Subclass: |
IgM |
| Applications: |
Western blot, Immunohistochemistry (frozen sections) |
| Immunogen: |
Synthetic peptides corresponding to 839-854 of the HRX protein |
| Reactivity: |
Human |
| Species raised in: |
Mouse |
| Fusion partner: |
NS-1 |
| Recommended growth conditions: |
RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| References: |
Butler LH, Slany R, Cui X, Cleary ML, Mason DY (1997) The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures. Blood 89:3361-3370.  |
| Notes: |
Please note this cell line has not been weaned out of HAT. Ultroser G can be used at 1% if the cells are not growing well |
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