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Anti-CD21 Antibody Profile

Antigen: CD21
Relevance: CD21 (Complement receptor type 2) is a cell surface receptor for C3d (CR2) and for EB-virus that links the innate and adaptive immune response during the activation of B cells. Soluble CD21, released from the plasma membrane blocks B cell/follicular dendritic cell interaction and activates monocytes.
Clone: BU32
Subclass: IgG1
Applications: FACS, Immunofluorescence, Immunohistochemistry (frozen sections), Immunohistology (mantle zone B cells, follicular dendritic cells)
Immunogen: Myeloma cell line Rob
Reactivity: Human
Species raised in: Mouse
Fusion partner: Non secreting plasmacytoma NSO/BALB/c mouse spleen cell; date of fusion: February 1987
Recommended growth conditions: RPMI 1640 + 10% FCS
References:

Knapp, W. et al. eds. 1989 Leucocyte Typing IV Oxford University

Leucocyte Typing III 1987 Oxford University Press

Leucocyte Typing V 1995 Oxford University Press

Leucocyte Typing VI 1998 Garland Publishing NY

Masilamani et al, Rheumatology 2004 43:186-90 PubMed Logo

Aubry, J.P. et al. 1992 Nature 358:505-507  PubMed Logo

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