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Anti Zebrafish Gut Secretory Cell Epitopes - Antibody Profile

Antigen: Zebrafish gut secretory cell epitopes
Relevance: The transparency of the juvenile zebrafish andits genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158). The antibody also labels hepatopancreatic ducts and intrahepatic bile ducts. enteroendocrine.
Clone: FIS 2F11/2
Subclass: IgG1
Applications: ELISA, Western, Immunoprecipitation, Immunofluoresence, Histology, Histocytochemistry
Immunogen: Lysate of zebrafish intestine
Reactivity: Zebrafish
Species raised in: Balb/c
Fusion partner: Sp2/OAg.14
References:

Cosnier et al. Development. 2005. 132: 1093-104 PubMed Logo

Dong et al. Nature Genetics. 2007. 39: 397-402 PubMed Logo

Bates et al. Developmental Biology. 2006. 297: 374-386 PubMed Logo

Matthews et al. Developmental Dynamics. 2008. 237: 124-131 PubMed Logo

Notes: Dilutions: WB 1:500
Will also stain formalin fixed tissue samples.

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