| Antigen: |
Zebrafish gut secretory cell epitopes |
| Relevance: |
The transparency of the juvenile zebrafish andits genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158). The antibody also labels hepatopancreatic ducts and intrahepatic bile ducts. enteroendocrine. |
| Clone: |
FIS 2F11/2 |
| Subclass: |
IgG1 |
| Applications: |
ELISA, Western, Immunoprecipitation, Immunofluoresence, Histology, Histocytochemistry |
| Immunogen: |
Lysate of zebrafish intestine |
| Reactivity: |
Zebrafish |
| Species raised in: |
Balb/c |
| Fusion partner: |
Sp2/OAg.14 |
| References: |
Cosnier et al. Development. 2005. 132: 1093-104 
Dong et al. Nature Genetics. 2007. 39: 397-402 
Bates et al. Developmental Biology. 2006. 297: 374-386 
Matthews et al. Developmental Dynamics. 2008. 237: 124-131  |
| Notes: |
Dilutions: WB 1:500
Will also stain formalin fixed tissue samples. |
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