| Antigen: |
Asf1 (anti-silencing function 1) |
| Relevance: |
Asf1 (anti-silencing function 1) belongs to the H3/H4 family of histone chaperones. Its function has not been fully elucidated but it is believed to be involved in ensuring a constant supply of histones at sites of nucleosome assembly. Asf1 interacts with the DNA damage checkpoint protein Rad53 and so may have a role in cell cycle regulation and DNA responses. ASF1 A and B (the two human subtypes) are the only known substrate for Tousled-like kinase (TLK). |
| Clone: |
ASF 4A1/3 |
| Subclass: |
IgG2a |
| Applications: |
Western blot |
| Immunogen: |
FLAG-ASF1A |
| Reactivity: |
Human and Mouse |
| Species raised in: |
Balb/c mouse |
| Fusion partner: |
sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM 5%FCS |
| References: |
- |
| Notes: |
Reacts with both ASF1A and ASF1B.
Recognises E coli and recombinant protein- has not been tested on endogenous protein |
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