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Anti-platelet complex IIb/IIIa Antibody Profile

Antigen: Platelet IIb/IIIa complex
Relevance: Glycoprotein complex IIb/IIIc is located on the platelet membrane but is connected through the cell membrane to the microfilament system
Clone: 189/21-10 (aka 85/661)
Subclass: IgG 2a
Applications: Immunoprecipitation, Immunocytochemistry(acetone fixed), Antigen capture ELISA for platelet antibody detection (MAIPA)
Immunogen: Human platelets
Reactivity: Human
Species raised in: Mouse: CBA
Fusion partner: NSO
Recommended growth conditions: RPMI 1640 + 5% FCS
References: Bird, C et al. 1986. Bioscience Reports. Vol 6. No. 3 p323-333. Clone cited as 85/661 PubMed Logo
Notes: 189/21-10 is human platelet specific; it does not recognise monocytes, polymorphonuclear leucocytes, lymphocytes, erythrocytes, leukaemic cell lines, fibroblast cell lines or rodent platelets

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