| Antigen: |
XPF |
| Relevance: |
Nucleotide excision repair (NER) is a DNA repair pathway that removes lesions induced by a variety of agents such as UV irradiation. ERCC1 binds to XPF to form the heterodimer ERCC1-XPF, which is a DNA endonuclease that is essential for the dual incision step of NER (cleaves 5' of the DNA lesion). |
| Clone: |
XPF 4H4 |
| Subclass: |
IgG1 |
| Applications: |
ELISA, Western, Immunofluorescence |
| Immunogen: |
A recombinant His-tagged fragment of human XPF protein produced in E. coli (amino acids 629-905 of XPF ) |
| Reactivity: |
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| Species raised in: |
Balb/c |
| Fusion partner: |
Sp2/0 Ag 14 |
| Recommended growth conditions: |
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| References: |
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| Notes: |
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