Testimonials

Small Molecules

Biological Therapeutics

New Targets

Diagnostics

Enabling Technology

Antibody Catalogue

Register

Privileged Access Section

Anti-EB1 Antibody Profile

Antigen: EB1
Relevance: EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex
Clone: 1A11/4
Subclass: IgG2b
Applications: ELISA, Western blot, Immunohistochemistry (methanol fixed)
Immunogen: EB1 deltaC1 mutant (see reference below)
Reactivity: Human, Monkey, Dog
Species raised in: Mouse CD-1
Fusion partner: Sp2/0 Ag.14
Recommended growth conditions: DMEM + 5% FCS
References: Description of the immunogen: Askham et al. 2002. Mol Biol Cell. 13: 3627-45 PubMed Logo
Notes:

This antibody recognises a defined epitope which is distinct from the major protein-protein interaction sites.   1A11/4 does not react with EB3 or RP1.  Positive control: HeLa cells

Image: Immunofluorescence in MDCK cells
 

For further information about antibodies from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com

Click here to view Notes and Disclaimer information

[back]